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Beschreibung
This book connects a retrosynthetic or disconnection approach with synthetic methods in the preparation of target molecules from simple, achiral ones to complex, chiral structures in the optically pure form. Retrosynthetic considerations and asymmetric syntheses are presented as closely related topics, often in the same chapter, underlining the importance of retrosynthetic consideration of target molecules neglecting stereochemistry and equipping readers to overcome the difficulties they may encounter in the planning and experimental implementation of asymmetric syntheses. This approach prepares students in advanced organic chemistry courses, and in particular young scientists working at academic and industrial laboratories, for independently solving synthetic problems and creating proposals for the synthesis of complex structures.
This book connects a retrosynthetic or disconnection approach with synthetic methods in the preparation of target molecules from simple, achiral ones to complex, chiral structures in the optically pure form. Retrosynthetic considerations and asymmetric syntheses are presented as closely related topics, often in the same chapter, underlining the importance of retrosynthetic consideration of target molecules neglecting stereochemistry and equipping readers to overcome the difficulties they may encounter in the planning and experimental implementation of asymmetric syntheses. This approach prepares students in advanced organic chemistry courses, and in particular young scientists working at academic and industrial laboratories, for independently solving synthetic problems and creating proposals for the synthesis of complex structures.
Zusammenfassung

Discusses methods and background information for the planning and implementation of stereoselective syntheses

Includes approx. 285 reaction schemes, 100 formulas for target molecules, and 20 figures

The author's expertise is based on over 30 years of experience in teaching organic synthesis and pursuing research in academia and industry

Includes supplementary material: [...]

Inhaltsverzeichnis
Foreword.- Introduction.- Retrosynthetic Analysis of compounds with one functional group.- Stereoisomers and stereoselective reactions - "Departure to the third dimension".- Disconnection by participation of two functional groups.- "Illogical" disconnections with participation of two groups.- Specific synthetic methodologies.- Retrosynthetic consideration of heterocyclic structures.- Retrosynthetic consideration of complex biologically active molecules.- Abbreviations and acronymes.- Subject index.
Details
Erscheinungsjahr: 2016
Fachbereich: Organische Chemie
Genre: Chemie, Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Naturwissenschaften & Technik
Medium: Buch
Inhalt: xiii
211 S.
378 s/w Illustr.
211 p. 378 illus.
ISBN-13: 9783319299242
ISBN-10: 3319299247
Sprache: Englisch
Herstellernummer: 978-3-319-29924-2
Einband: Gebunden
Autor: Petrovi¿ Perokovi¿, Vesna
¿Unji¿, Vitomir
Auflage: 1st edition 2016
Hersteller: Springer International Publishing
Springer International Publishing AG
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße: 241 x 160 x 18 mm
Von/Mit: Vesna Petrovi¿ Perokovi¿ (u. a.)
Erscheinungsdatum: 10.05.2016
Gewicht: 0,512 kg
Artikel-ID: 104028969

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