Hong-Gang Wang: Autophagy and Cancer

Cover: 9781461465607 | Autophagy and Cancer | Hong-Gang Wang | Buch | xi | Englisch | 2013

Rückseite: 9781461465607 | Autophagy and Cancer | Hong-Gang Wang | Buch | xi | Englisch | 2013

Dekorationsartikel gehören nicht zum Leistungsumfang.

Sprache: Englisch

134,95 €

-16 % UVP 160,49 €

inkl. MwSt.

Versandkostenfrei per Post / DHL

Lieferzeit 1-2 Wochen

Kategorien:

Beschreibung

With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy ¿ what to target and how to target it. ¿

Über den Autor

Dr. Hong-Gang Wang is the Lois High Berstler Professor, Department of Pharmacology at Penn State College of Medicine. Dr. Wang is a leading research scientist in the area of autophagy and cancer.

Zusammenfassung

Summarizes the key players that function in autophagosome formation, elongation and maturation? and its involvement in cancer progression

Provides latest research of how autophagy is regulated

Explores the roles of autophagy in tumorigenesis?

Includes supplementary material: [...]

Inhaltsverzeichnis

Preface.- ¿¿Historical Overview of Autophagy.- The Core Molecular Machinery of Autophagosome Formation.- The origin of autophagosomes: The beginning of an end.- Signal Transduction Regulation of Autophagy.- Role of Autophagy in Tumorigenesis.- Selective autophagy and cancer.- Oncogenes and tumor suppressor genes in autophagy.- Autophagy and Immunity.- Autophagy and the Tumor Microenvironment.- Autophagy and Cancer Therapy.- The Crosstalk between Apoptosis & Autophagy.- Autophagy and Cancer Drug Discovery.- Index.

Details

Erscheinungsjahr:	2013
Fachbereich:	Therapie
Genre:	Importe , Medizin
Rubrik:	Wissenschaften
Medium:	Buch
Inhalt:	xi 261 S.
ISBN-13:	9781461465607
ISBN-10:	1461465605
Sprache:	Englisch
Einband:	Gebunden
Redaktion:	Wang, Hong-Gang
Herausgeber:	Hong-Gang Wang
Hersteller:	Springer US Springer New York
Verantwortliche Person für die EU:	Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße:	241 x 160 x 18 mm
Von/Mit:	Hong-Gang Wang
Erscheinungsdatum:	30.03.2013
Gewicht:	0,582 kg