Introduction

PART 1: DESGIN OF CPPS
Classification of cell-penetrating peptides
Arginine-rich cell-penetrating peptides: recent advances of design and applications for intracellular delivery
Cationic cell-penetrating peptides
Amphipathic cell-penetrating peptides
Hydrophobic cell-penetrating peptides
Foldamers

PART 2: MECHANISM OF CPPS
Peptide Structure: Electrophysiological analysis, nuclear magnetic resonance analysis, and molecular dynamics simulation of direct penetration of cell-penetrating peptides through bilayer lipid membranes
Cellular uptake mechanisms of arginine-rich cell-penetrating peptides
Endosomal escape
Pharmacokinetics of therapeutic and diagnostic agents conjugated with cell-penetrating peptides

PART 3: DELIVERY TOOLS
Drug delivery
Peptide & protein delivery
Cell-penetrating peptides for nucleic acid delivery
PPMOs: a case study for cell-penetrating peptide application
Cell penetrating peptide-conjugated polymer micelles for pDNA/siRNA delivery
Lipid-based nanoparticles using cell-penetrating peptides

PART 4: APPLICATIONS
Cell-penetrating peptides as tools to facilitate oral delivery of biopharmaceuticals
Intranasal delivery
Clinical trials
Applications in plants