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This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.
This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.
| Erscheinungsjahr: | 2012 |
|---|---|
| Fachbereich: | Physikalische Chemie |
| Genre: | Chemie, Importe |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Buch |
| Inhalt: | Gebunden |
| ISBN-13: | 9781848166349 |
| ISBN-10: | 1848166346 |
| Sprache: | Englisch |
| Einband: | Gebunden |
| Autor: | Veronique Gouverneur & Klaus Muller |
| Redaktion: |
Gouverneur, Veronique
Muller, Klaus |
| Hersteller: | ICP |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 235 x 157 x 35 mm |
| Von/Mit: | Veronique Gouverneur & Klaus Muller |
| Erscheinungsdatum: | 26.04.2012 |
| Gewicht: | 0,969 kg |
| Erscheinungsjahr: | 2012 |
|---|---|
| Fachbereich: | Physikalische Chemie |
| Genre: | Chemie, Importe |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Buch |
| Inhalt: | Gebunden |
| ISBN-13: | 9781848166349 |
| ISBN-10: | 1848166346 |
| Sprache: | Englisch |
| Einband: | Gebunden |
| Autor: | Veronique Gouverneur & Klaus Muller |
| Redaktion: |
Gouverneur, Veronique
Muller, Klaus |
| Hersteller: | ICP |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 235 x 157 x 35 mm |
| Von/Mit: | Veronique Gouverneur & Klaus Muller |
| Erscheinungsdatum: | 26.04.2012 |
| Gewicht: | 0,969 kg |
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