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Formulation & Development of Rosuvastatin Fast Dissolving Tablets
Formulation Design of Rosuvastatin
Taschenbuch von Kurra Venkata Gopaiah
Sprache: Englisch

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Beschreibung
Floating systems or hydrodynamically controlled systems are low-density systems that have sufficient buoyancy to float over the gastric contents and remain buoyant in the stomach without affecting the gastric emptying rate for a prolonged period of time. While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the system. After the release of the drug, the residual system is emptied from the stomach. This results in an increased GRT and better control of the fluctuations in plasma drug concentration. However, besides a minimal gastric content needed to allow the proper achievement of the buoyancy retention principle, a minimal level of floating force (F) is also required to keep the dosage form reliably buoyant on the surface of the meal. Many buoyant systems have been developed based on granules, powders, capsules, tablets, laminated films, and hollow microspheres.
Floating systems or hydrodynamically controlled systems are low-density systems that have sufficient buoyancy to float over the gastric contents and remain buoyant in the stomach without affecting the gastric emptying rate for a prolonged period of time. While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the system. After the release of the drug, the residual system is emptied from the stomach. This results in an increased GRT and better control of the fluctuations in plasma drug concentration. However, besides a minimal gastric content needed to allow the proper achievement of the buoyancy retention principle, a minimal level of floating force (F) is also required to keep the dosage form reliably buoyant on the surface of the meal. Many buoyant systems have been developed based on granules, powders, capsules, tablets, laminated films, and hollow microspheres.
Über den Autor
The author currently working as Assistant Professor in K L E F, K L College of Pharmacy, Guntur. Submitted thesis work for Ph.D. to JAIPUR NATIONAL UNIVERSITY-JAIPUR. Attended and participated in various National & International Conferences, Seminar & also act as Scientific Evaluator in various National & International Conferences.
Details
Erscheinungsjahr: 2019
Fachbereich: Toxikologie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
ISBN-13: 9786200473011
ISBN-10: 6200473013
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Gopaiah, Kurra Venkata
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: preigu, Ansas Meyer, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de
Maße: 220 x 150 x 4 mm
Von/Mit: Kurra Venkata Gopaiah
Erscheinungsdatum: 09.12.2019
Gewicht: 0,113 kg
Artikel-ID: 120469503
Über den Autor
The author currently working as Assistant Professor in K L E F, K L College of Pharmacy, Guntur. Submitted thesis work for Ph.D. to JAIPUR NATIONAL UNIVERSITY-JAIPUR. Attended and participated in various National & International Conferences, Seminar & also act as Scientific Evaluator in various National & International Conferences.
Details
Erscheinungsjahr: 2019
Fachbereich: Toxikologie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
ISBN-13: 9786200473011
ISBN-10: 6200473013
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Gopaiah, Kurra Venkata
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: preigu, Ansas Meyer, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de
Maße: 220 x 150 x 4 mm
Von/Mit: Kurra Venkata Gopaiah
Erscheinungsdatum: 09.12.2019
Gewicht: 0,113 kg
Artikel-ID: 120469503
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