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Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD).
It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.
Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD).
It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.
Erscheinungsjahr: | 2016 |
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Fachbereich: | Andere Fachgebiete |
Genre: | Medizin |
Rubrik: | Wissenschaften |
Medium: | Taschenbuch |
Inhalt: | Kartoniert / Broschiert |
ISBN-13: | 9780128044681 |
ISBN-10: | 0128044683 |
Sprache: | Englisch |
Herstellernummer: | C2014-0-04358-4 |
Autor: |
Lejeune, Fabrice
Benhabiles, Hana Jia, Jieshuang |
Hersteller: | Academic Press |
Verantwortliche Person für die EU: | preigu, Ansas Meyer, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de |
Maße: | 9 x 152 x 229 mm |
Von/Mit: | Fabrice Lejeune (u. a.) |
Erscheinungsdatum: | 21.04.2016 |
Gewicht: | 0,316 kg |
Erscheinungsjahr: | 2016 |
---|---|
Fachbereich: | Andere Fachgebiete |
Genre: | Medizin |
Rubrik: | Wissenschaften |
Medium: | Taschenbuch |
Inhalt: | Kartoniert / Broschiert |
ISBN-13: | 9780128044681 |
ISBN-10: | 0128044683 |
Sprache: | Englisch |
Herstellernummer: | C2014-0-04358-4 |
Autor: |
Lejeune, Fabrice
Benhabiles, Hana Jia, Jieshuang |
Hersteller: | Academic Press |
Verantwortliche Person für die EU: | preigu, Ansas Meyer, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de |
Maße: | 9 x 152 x 229 mm |
Von/Mit: | Fabrice Lejeune (u. a.) |
Erscheinungsdatum: | 21.04.2016 |
Gewicht: | 0,316 kg |