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Cover: 9783031050008 | Polypharmacology | Principles and Methodologies | Baofeng Yang (u. a.)
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Polypharmacology
Principles and Methodologies
Taschenbuch von Baofeng Yang (u. a.)
Sprache: Englisch

145,95 €*

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Über den Autor
Zhiguo Wang PhD received his PhD in cardiovascular pharmacology from McGill University, Canada. He is presently the Director of the Division of Drug Discovery, Meditech Institute of Research and Advance (USA) and a Distinguished Professor in the Department of Pharmacology, Harbin Medical University. He is an author of over 150 research articles in prestigious scientific journals and of 6 monographs and 15 book chapters with renowned scientific publishers. His research interests cover cardiovascular disease and pharmacology, molecular pharmacology, epigenetic polypharmacology. His research group is one of the earliest investigators who proposed "one drug, multiple targets" polypharmacology concept and provided the experimental evidence in support of the epigenetic polypharmacology.
Inhaltsverzeichnis
PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles.- Basics of Polypharmacology.- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C).- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF).- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD).-Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD.- Anti-cancer Polypharmacology.- Cardiovascular Polypharmacology.- Neuronal Polypharmacology.- Pulmonary Polypharmacology.- Polypharmacology of Metabolic Disease.- Polypharmacology of Infectious Disease.- Polypharmacology of Inflammation.- Anti-psychotics Polypharmacology.- Anti-aging Polypharmacology.- Polypharmacology in Drug Repurposing.-Polypharmacology and Unintended Drug Promiscuity.- Polypharmacology Pharmacokinetics.- The Future of Polypharmacology.- PART II. Polypharmacology in New Drug Development: Strategies and Protocols.- Designed MTSD Discovery Process.- Designed MTSD Discovery Strategies.- Designed MTSD Discovery Technologies.- Designed MTSD Discovery Databases.- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation.-Designed MTSD Lead Identification and Optimization.- Designed MTSD Discovery Protocols.- Natural Products in MTSD Discovery.- Polypharmacology Procedures for Drug Repurposing.- Polypharmacology Procedures for Drug Promiscuity Discovery.
Details
Erscheinungsjahr: 2023
Fachbereich: Toxikologie
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Inhalt: 2 Taschenbücher
ISBN-13: 9783031050008
ISBN-10: 3031050002
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Yang, Baofeng
Wang, Zhiguo
Hersteller: Springer International Publishing
Springer International Publishing AG
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße: 254 x 178 x 50 mm
Von/Mit: Baofeng Yang (u. a.)
Erscheinungsdatum: 03.08.2023
Gewicht: 1,702 kg
Artikel-ID: 127243573
Über den Autor
Zhiguo Wang PhD received his PhD in cardiovascular pharmacology from McGill University, Canada. He is presently the Director of the Division of Drug Discovery, Meditech Institute of Research and Advance (USA) and a Distinguished Professor in the Department of Pharmacology, Harbin Medical University. He is an author of over 150 research articles in prestigious scientific journals and of 6 monographs and 15 book chapters with renowned scientific publishers. His research interests cover cardiovascular disease and pharmacology, molecular pharmacology, epigenetic polypharmacology. His research group is one of the earliest investigators who proposed "one drug, multiple targets" polypharmacology concept and provided the experimental evidence in support of the epigenetic polypharmacology.
Inhaltsverzeichnis
PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles.- Basics of Polypharmacology.- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C).- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF).- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD).-Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD.- Anti-cancer Polypharmacology.- Cardiovascular Polypharmacology.- Neuronal Polypharmacology.- Pulmonary Polypharmacology.- Polypharmacology of Metabolic Disease.- Polypharmacology of Infectious Disease.- Polypharmacology of Inflammation.- Anti-psychotics Polypharmacology.- Anti-aging Polypharmacology.- Polypharmacology in Drug Repurposing.-Polypharmacology and Unintended Drug Promiscuity.- Polypharmacology Pharmacokinetics.- The Future of Polypharmacology.- PART II. Polypharmacology in New Drug Development: Strategies and Protocols.- Designed MTSD Discovery Process.- Designed MTSD Discovery Strategies.- Designed MTSD Discovery Technologies.- Designed MTSD Discovery Databases.- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation.-Designed MTSD Lead Identification and Optimization.- Designed MTSD Discovery Protocols.- Natural Products in MTSD Discovery.- Polypharmacology Procedures for Drug Repurposing.- Polypharmacology Procedures for Drug Promiscuity Discovery.
Details
Erscheinungsjahr: 2023
Fachbereich: Toxikologie
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Inhalt: 2 Taschenbücher
ISBN-13: 9783031050008
ISBN-10: 3031050002
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Yang, Baofeng
Wang, Zhiguo
Hersteller: Springer International Publishing
Springer International Publishing AG
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße: 254 x 178 x 50 mm
Von/Mit: Baofeng Yang (u. a.)
Erscheinungsdatum: 03.08.2023
Gewicht: 1,702 kg
Artikel-ID: 127243573
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