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Specimen collection, preservation, and testing options are thoroughly discussed, from the routine ova and parasite examination to blood films, fecal immunoassays, and the newer molecular test panels. Specific test procedures, laboratory methods and reagents, and algorithms are provided. The ever-helpful "FAQ" section of commonly asked questions now offers expanded information on stool specimen fixatives and testing, thorough coverage of new techniques, and advice on reporting and commenting on results.
The heart of the Guide, covering identification of individual pathogens, has been expanded with more discussion and comparison of organisms and dozens of new color images. An entirely new section has been added that uses extensive figures and new tables to illustrate common problems with differentiating organisms from one another and from possible microscopic artifacts. The final section has been reorganized to include identification keys and dozens of tables summarizing organism characteristics to assist the bench microbiologist with routine diagnostic testing methods.
If you are looking for online access to the latest clinical microbiology content, please visit [...]
Specimen collection, preservation, and testing options are thoroughly discussed, from the routine ova and parasite examination to blood films, fecal immunoassays, and the newer molecular test panels. Specific test procedures, laboratory methods and reagents, and algorithms are provided. The ever-helpful "FAQ" section of commonly asked questions now offers expanded information on stool specimen fixatives and testing, thorough coverage of new techniques, and advice on reporting and commenting on results.
The heart of the Guide, covering identification of individual pathogens, has been expanded with more discussion and comparison of organisms and dozens of new color images. An entirely new section has been added that uses extensive figures and new tables to illustrate common problems with differentiating organisms from one another and from possible microscopic artifacts. The final section has been reorganized to include identification keys and dozens of tables summarizing organism characteristics to assist the bench microbiologist with routine diagnostic testing methods.
If you are looking for online access to the latest clinical microbiology content, please visit [...]
Lynne Shore Garcia is the director of LSG & Associates, a firm providing training, teaching, and consultation services for diagnostic medical parasitology and health care administration. A former manager of the UCLA Clinical Microbiology Laboratory, she is a sought-after speaker (nationally and internationally) and author of hundreds of articles, book chapters, and books including two ASM Press books, Clinical Laboratory Management, Second Edition and Diagnostic Medical Parasitology, Sixth Edition.
Preface xix
About the Author xxiii
Section 1 Philosophy and Approach to Diagnostic Parasitology 1
Neglected Tropical Diseases 2
Why Perform Diagnostic Parasitology Testing? 3
Travel 3
Population Movements 3
Control Issues 4
Climate Change 4
Epidemiologic Considerations 4
Compromised Patients; Potential Sex Bias Regarding Infection Susceptibility; Aging 4
Approach to Therapy 5
Who Should Perform Diagnostic Parasitology Testing? 5
Laboratory Personnel 5
Nonlaboratory Personnel 5
Where Should Diagnostic Parasitology Testing Be Performed? 6
Inpatient Setting 6
Outpatient or Referral Setting 6
Decentralized Testing 6
Physician Office Laboratories 6
Over-the-Counter (Home Care) Testing 7
Field Sites 7
What Factors Should Precipitate Testing? 7
Travel and Residence History 7
Immune Status of the Patient 7
Clinical Symptoms 7
Documented Previous Infection 7
Contact with Infected Individuals 8
Potential Outbreak Testing 8
Occupational Testing 8
Therapeutic Failure 8
What Testing Should Be Performed? 8
Routine Tests 8
Special Testing and Reference Laboratories 9
Specialized Referral Test Options-DPDx and Other Sites 9
Other (Nonmicrobiological) Testing 10
What Factors Should Be Considered in Development of Test Menus? 10
Physical Plant 10
Client Base 10
Customer Requirements and Perceived Levels of Service 10
Personnel Availability and Level of Expertise 10
Equipment 10
Budget 11
Risk Management Issues Associated with Stat Testing 11
Primary Amebic Meningoencephalitis 11
Granulomatous Amebic Encephalitis and Amebic Keratitis 14
Request for Blood Films 15
Automated Instrumentation 15
Patient Information 16
Conventional Microscopy 16
Table 1.1 Common features of the neglected tropical diseases 18
Section 2 Parasite Classification and Relevant Body Sites 19
Protozoa (Intestinal) 20
Amebae, Stramenopiles 20
Flagellates 22
Ciliates 22
Apicomplexa (Including Coccidia) 23
Microsporidia (Now Classified with the Fungi) 23
Protozoa (Other Body Sites) 24
Amebae 24
Flagellates 24
Apicomplexa (Including Coccidia) 24
Microsporidia (Now Classified with the Fungi) 25
Protozoa (Blood and Tissue) 26
Apicomplexa (Including Sporozoa) 26
Flagellates 26
Nematodes (Intestinal) 29
Nematodes (Tissue) 29
Nematodes (Blood and Tissue) 30
Cestodes (Intestinal) 31
Cestodes (Tissue) 32
Trematodes (Intestinal) 33
Trematodes (Liver and Lungs) 33
Trematodes (Blood) 35
Pentastomids 35
Acanthocephala 36
Table 2.1 Classification of human parasites 37
Table 2.2 Cosmopolitan distribution of common parasitic infections 39
Table 2.3 Body sites and possible parasites recovered 40
Section 3 Collection Options 43
Safety 44
Collection of Fresh Stool Specimens 44
Collection Method 44
Number of Specimens To Be Collected 45
Collection Times 47
Posttherapy Collection 47
Specimen Type, Stability, and Need for Preservation 47
Preservation of Stool Specimens 48
Overview of Preservatives 48
Formalin 49
Sodium Acetate-Acetic Acid-Formalin (SAF) 50
Schaudinn's Fluid 51
Schaudinn's Fluid containing PVA (Mercury Base) 52
Schaudinn's Fluid containing PVA (Copper Base, Zinc Base) 52
Single-Vial Collection Systems (Other than SAF) 53
Universal Fixative (Total-Fix) 54
Quality Control for Preservatives 54
Procedure Notes for Use of Preservatives (Stool Fixative Collection Vials) 55
Procedure Limitations for Use of Preservatives (Stool Fixative Collection Vials) 55
Collection of Blood 56
Collection and Processing 56
Stat Test Requests and Risk Management Issues 57
Collection of Specimens from Other Body Sites 57
Table 3.1 Fecal specimens for parasites: options for collection and processing 58
Table 3.2 Approaches to stool parasitology: test ordering 61
Table 3.3 Preservatives and procedures commonly used in diagnostic parasitology (stool specimens) 62
Table 3.4 Advantages of thin and thick blood films 64
Table 3.5 Advantages and disadvantages of buffy coat films 64
Table 3.6 Potential problems of using EDTA anticoagulant for the preparation of thin and thick blood films 65
Table 3.7 Body sites and possible parasites recovered (trophozoites, cysts, oocysts, spores, adults, larvae, eggs, amastigotes, and trypomastigotes) 66
Section 4 Specimen Test Options: Routine Diagnostic Methods and Body Sites 69
Ova and Parasite Examination of Stool Specimens 70
Other Diagnostic Methods for Stool Specimens 72
Culture of Larval-Stage Nematodes 72
Estimation of Worm Burdens through Egg Counts 73
Hatching Test for Schistosome Eggs 73
Screening Stool Samples for Recovery of a Tapeworm Scolex 74
Testing of Other Intestinal Tract Specimens 74
Examination for Pinworm 74
Sigmoidoscopy Material 75
Duodenal Drainage Material 76
Duodenal Capsule Technique (Entero-Test) 76
Urogenital Tract Specimens 77
Sputum 77
Aspirates 78
Biopsy Specimens 78
Blood 79
Thin Blood Films 79
Thick Blood Films 80
Blood Staining Methods 80
Buffy Coat Films 80
QBC Microhematocrit Centrifugation Method 80
Knott Concentration 81
Membrane Filtration Technique 81
Culture Methods 81
Animal Inoculation and Xenodiagnosis 82
Antibody and Antigen Detection 82
Antibody Detection 82
Antigen Detection, Nucleic Acid-Based Tests, and Molecular Panels 84
Intradermal Tests 84
UV Autofluorescence 84
Table 4.1 Body sites, procedures and specimens, recommended methods and relevant parasites, and comments 86
Table 4.2 Serologic, antigen, and probe tests used in the diagnosis of parasitic infections 94
Section 5 Specific Test Procedures and Algorithms 95
Microscopy 96
CALIBRATION OF THE MICROSCOPE 96
Ova and Parasite Examination 99
DIRECT WET FECAL SMEAR 99
CONCENTRATION (Sedimentation and Flotation) 104
SEDIMENTATION CONCENTRATION (Formalin-Ethyl Acetate) 105
SEDIMENTATION CONCENTRATION USING THE UNIVERSAL FIXATIVE (Total-Fix) 109
FLOTATION CONCENTRATION (Zinc Sulfate) 110
PERMANENT STAINED SMEAR 114
Stains Used in the Permanent Stained Smear 116
TRICHROME STAIN (Wheatley's Method) 116
IRON HEMATOXYLIN STAIN (Spencer-Monroe Method) 122
IRON HEMATOXYLIN STAIN (Tompkins-Miller Method) 127
MODIFIED IRON HEMATOXYLIN STAIN (Incorporating the Carbol Fuchsin Step) 128
CHLORAZOL BLACK E STAIN 131
Specialized Stains for Coccidia and Microsporidia 132
KINYOUN'S ACID-FAST STAIN (Cold Method) 132
MODIFIED ZIEHL-NEELSEN ACID-FAST STAIN (Hot Method) 136
CARBOL FUCHSIN NEGATIVE STAIN FOR CRYPTOSPORIDIUM (W. L. Current) 139
RAPID SAFRANIN METHOD FOR CRYPTOSPORIDIUM (D. Baxby) 139
RAPID SAFRANIN METHOD FOR CYCLOSPORA, USING A MICROWAVE OVEN (Govinda Visvesvara) 139
AURAMINE O STAIN FOR APLICOMPLEXA (INCLUDING COCCIDIA) (Thomas Hänscheid) 140
MODIFIED TRICHROME STAIN FOR MICROSPORIDIA (Weber, Green Counterstain) 144
MODIFIED TRICHROME STAIN FOR MICROSPORIDIA (Ryan, Blue Counterstain) 146
MODIFIED TRICHROME STAIN FOR MICROSPORIDIA (Evelyn Kokoskin, Hot Method) 149
Fecal Immunoassays for Intestinal Protozoa 150
ENTAMOEBA HISTOLYTICA 150
CRYPTOSPORIDIUM SPP. 151
GIARDIA LAMBLIA 151
KITS UNDER DEVELOPMENT 151
COMMENTS ON THE PERFORMANCE OF FECAL IMMUNOASSAYS 151
ENZYME IMMUNOASSAYS (Antigen Detection, No Centrifugation Recommended) 152
FLUORESCENCE (Visual Identification of the Organisms, Centrifugation Recommended) 152
LATERAL-FLOW CARTRIDGES (Antigen Detection, No Centrifugation Recommended) 153
Larval Nematode Culture 153
HARADA-MORI FILTER PAPER STRIP CULTURE 153
BAERMANN CONCENTRATION 155
AGAR PLATE CULTURE FOR STRONGYLOIDES STERCORALIS 158
Other Methods for Gastrointestinal Tract Specimens 161
EXAMINATION FOR PINWORM (Cellulose Tape Preparations) 161
SIGMOIDOSCOPY SPECIMENS (Direct Wet Smear) 163
SIGMOIDOSCOPY SPECIMENS (Permanent Stained Smear) 166
DUODENAL ASPIRATES 168
Methods for Urogenital Tract Specimens 171
RECEIPT OF DRY SMEARS 171
DIRECT SALINE MOUNT 171
PERMANENT STAINED SMEAR 174
URINE CONCENTRATION (Centrifugation) 176
URINE CONCENTRATION (Nuclepore Membrane Filter) 179
Preparation of Blood Films 181
THIN BLOOD FILMS 182
THICK BLOOD FILMS 184
COMBINATION THICK-THIN BLOOD FILMS 186
RISK MANAGEMENT ISSUES ASSOCIATED WITH BLOOD FILMS 187
USE OF A REFERENCE LABORATORY FOR PARASITE BLOOD DIAGNOSTIC TESTING 188
BLOOD FILM REPORTING WITH ADDITIONAL REPORT COMMENTS 189
BUFFY COAT BLOOD FILMS 189
Blood Stains 190
STAIN OPTIONS 190
GIEMSA STAIN 190
Blood Concentration 194
BUFFY COAT CONCENTRATION 194
KNOTT CONCENTRATION 195
MEMBRANE FILTRATION CONCENTRATION 197
Algorithm 5.1 Procedure for processing fresh stool for the O&P examination 201
Algorithm 5.2 Procedure for processing liquid specimens for the O&P examination 202
...Erscheinungsjahr: | 2021 |
---|---|
Fachbereich: | Tiermedizin |
Genre: | Importe, Medizin |
Rubrik: | Wissenschaften |
Medium: | Taschenbuch |
Inhalt: | 592 S. |
ISBN-13: | 9781683670391 |
ISBN-10: | 1683670396 |
Sprache: | Englisch |
Einband: | Kartoniert / Broschiert |
Autor: | Garcia, Lynne Shore |
Redaktion: | Garcia, Lynne Shore |
Auflage: | 3rd edition |
Hersteller: | Wiley |
Verantwortliche Person für die EU: | Wiley-VCH GmbH, Boschstr. 12, D-69469 Weinheim, product-safety@wiley.com |
Maße: | 253 x 178 x 27 mm |
Von/Mit: | Lynne Shore Garcia |
Erscheinungsdatum: | 22.06.2021 |
Gewicht: | 1,226 kg |
Lynne Shore Garcia is the director of LSG & Associates, a firm providing training, teaching, and consultation services for diagnostic medical parasitology and health care administration. A former manager of the UCLA Clinical Microbiology Laboratory, she is a sought-after speaker (nationally and internationally) and author of hundreds of articles, book chapters, and books including two ASM Press books, Clinical Laboratory Management, Second Edition and Diagnostic Medical Parasitology, Sixth Edition.
Preface xix
About the Author xxiii
Section 1 Philosophy and Approach to Diagnostic Parasitology 1
Neglected Tropical Diseases 2
Why Perform Diagnostic Parasitology Testing? 3
Travel 3
Population Movements 3
Control Issues 4
Climate Change 4
Epidemiologic Considerations 4
Compromised Patients; Potential Sex Bias Regarding Infection Susceptibility; Aging 4
Approach to Therapy 5
Who Should Perform Diagnostic Parasitology Testing? 5
Laboratory Personnel 5
Nonlaboratory Personnel 5
Where Should Diagnostic Parasitology Testing Be Performed? 6
Inpatient Setting 6
Outpatient or Referral Setting 6
Decentralized Testing 6
Physician Office Laboratories 6
Over-the-Counter (Home Care) Testing 7
Field Sites 7
What Factors Should Precipitate Testing? 7
Travel and Residence History 7
Immune Status of the Patient 7
Clinical Symptoms 7
Documented Previous Infection 7
Contact with Infected Individuals 8
Potential Outbreak Testing 8
Occupational Testing 8
Therapeutic Failure 8
What Testing Should Be Performed? 8
Routine Tests 8
Special Testing and Reference Laboratories 9
Specialized Referral Test Options-DPDx and Other Sites 9
Other (Nonmicrobiological) Testing 10
What Factors Should Be Considered in Development of Test Menus? 10
Physical Plant 10
Client Base 10
Customer Requirements and Perceived Levels of Service 10
Personnel Availability and Level of Expertise 10
Equipment 10
Budget 11
Risk Management Issues Associated with Stat Testing 11
Primary Amebic Meningoencephalitis 11
Granulomatous Amebic Encephalitis and Amebic Keratitis 14
Request for Blood Films 15
Automated Instrumentation 15
Patient Information 16
Conventional Microscopy 16
Table 1.1 Common features of the neglected tropical diseases 18
Section 2 Parasite Classification and Relevant Body Sites 19
Protozoa (Intestinal) 20
Amebae, Stramenopiles 20
Flagellates 22
Ciliates 22
Apicomplexa (Including Coccidia) 23
Microsporidia (Now Classified with the Fungi) 23
Protozoa (Other Body Sites) 24
Amebae 24
Flagellates 24
Apicomplexa (Including Coccidia) 24
Microsporidia (Now Classified with the Fungi) 25
Protozoa (Blood and Tissue) 26
Apicomplexa (Including Sporozoa) 26
Flagellates 26
Nematodes (Intestinal) 29
Nematodes (Tissue) 29
Nematodes (Blood and Tissue) 30
Cestodes (Intestinal) 31
Cestodes (Tissue) 32
Trematodes (Intestinal) 33
Trematodes (Liver and Lungs) 33
Trematodes (Blood) 35
Pentastomids 35
Acanthocephala 36
Table 2.1 Classification of human parasites 37
Table 2.2 Cosmopolitan distribution of common parasitic infections 39
Table 2.3 Body sites and possible parasites recovered 40
Section 3 Collection Options 43
Safety 44
Collection of Fresh Stool Specimens 44
Collection Method 44
Number of Specimens To Be Collected 45
Collection Times 47
Posttherapy Collection 47
Specimen Type, Stability, and Need for Preservation 47
Preservation of Stool Specimens 48
Overview of Preservatives 48
Formalin 49
Sodium Acetate-Acetic Acid-Formalin (SAF) 50
Schaudinn's Fluid 51
Schaudinn's Fluid containing PVA (Mercury Base) 52
Schaudinn's Fluid containing PVA (Copper Base, Zinc Base) 52
Single-Vial Collection Systems (Other than SAF) 53
Universal Fixative (Total-Fix) 54
Quality Control for Preservatives 54
Procedure Notes for Use of Preservatives (Stool Fixative Collection Vials) 55
Procedure Limitations for Use of Preservatives (Stool Fixative Collection Vials) 55
Collection of Blood 56
Collection and Processing 56
Stat Test Requests and Risk Management Issues 57
Collection of Specimens from Other Body Sites 57
Table 3.1 Fecal specimens for parasites: options for collection and processing 58
Table 3.2 Approaches to stool parasitology: test ordering 61
Table 3.3 Preservatives and procedures commonly used in diagnostic parasitology (stool specimens) 62
Table 3.4 Advantages of thin and thick blood films 64
Table 3.5 Advantages and disadvantages of buffy coat films 64
Table 3.6 Potential problems of using EDTA anticoagulant for the preparation of thin and thick blood films 65
Table 3.7 Body sites and possible parasites recovered (trophozoites, cysts, oocysts, spores, adults, larvae, eggs, amastigotes, and trypomastigotes) 66
Section 4 Specimen Test Options: Routine Diagnostic Methods and Body Sites 69
Ova and Parasite Examination of Stool Specimens 70
Other Diagnostic Methods for Stool Specimens 72
Culture of Larval-Stage Nematodes 72
Estimation of Worm Burdens through Egg Counts 73
Hatching Test for Schistosome Eggs 73
Screening Stool Samples for Recovery of a Tapeworm Scolex 74
Testing of Other Intestinal Tract Specimens 74
Examination for Pinworm 74
Sigmoidoscopy Material 75
Duodenal Drainage Material 76
Duodenal Capsule Technique (Entero-Test) 76
Urogenital Tract Specimens 77
Sputum 77
Aspirates 78
Biopsy Specimens 78
Blood 79
Thin Blood Films 79
Thick Blood Films 80
Blood Staining Methods 80
Buffy Coat Films 80
QBC Microhematocrit Centrifugation Method 80
Knott Concentration 81
Membrane Filtration Technique 81
Culture Methods 81
Animal Inoculation and Xenodiagnosis 82
Antibody and Antigen Detection 82
Antibody Detection 82
Antigen Detection, Nucleic Acid-Based Tests, and Molecular Panels 84
Intradermal Tests 84
UV Autofluorescence 84
Table 4.1 Body sites, procedures and specimens, recommended methods and relevant parasites, and comments 86
Table 4.2 Serologic, antigen, and probe tests used in the diagnosis of parasitic infections 94
Section 5 Specific Test Procedures and Algorithms 95
Microscopy 96
CALIBRATION OF THE MICROSCOPE 96
Ova and Parasite Examination 99
DIRECT WET FECAL SMEAR 99
CONCENTRATION (Sedimentation and Flotation) 104
SEDIMENTATION CONCENTRATION (Formalin-Ethyl Acetate) 105
SEDIMENTATION CONCENTRATION USING THE UNIVERSAL FIXATIVE (Total-Fix) 109
FLOTATION CONCENTRATION (Zinc Sulfate) 110
PERMANENT STAINED SMEAR 114
Stains Used in the Permanent Stained Smear 116
TRICHROME STAIN (Wheatley's Method) 116
IRON HEMATOXYLIN STAIN (Spencer-Monroe Method) 122
IRON HEMATOXYLIN STAIN (Tompkins-Miller Method) 127
MODIFIED IRON HEMATOXYLIN STAIN (Incorporating the Carbol Fuchsin Step) 128
CHLORAZOL BLACK E STAIN 131
Specialized Stains for Coccidia and Microsporidia 132
KINYOUN'S ACID-FAST STAIN (Cold Method) 132
MODIFIED ZIEHL-NEELSEN ACID-FAST STAIN (Hot Method) 136
CARBOL FUCHSIN NEGATIVE STAIN FOR CRYPTOSPORIDIUM (W. L. Current) 139
RAPID SAFRANIN METHOD FOR CRYPTOSPORIDIUM (D. Baxby) 139
RAPID SAFRANIN METHOD FOR CYCLOSPORA, USING A MICROWAVE OVEN (Govinda Visvesvara) 139
AURAMINE O STAIN FOR APLICOMPLEXA (INCLUDING COCCIDIA) (Thomas Hänscheid) 140
MODIFIED TRICHROME STAIN FOR MICROSPORIDIA (Weber, Green Counterstain) 144
MODIFIED TRICHROME STAIN FOR MICROSPORIDIA (Ryan, Blue Counterstain) 146
MODIFIED TRICHROME STAIN FOR MICROSPORIDIA (Evelyn Kokoskin, Hot Method) 149
Fecal Immunoassays for Intestinal Protozoa 150
ENTAMOEBA HISTOLYTICA 150
CRYPTOSPORIDIUM SPP. 151
GIARDIA LAMBLIA 151
KITS UNDER DEVELOPMENT 151
COMMENTS ON THE PERFORMANCE OF FECAL IMMUNOASSAYS 151
ENZYME IMMUNOASSAYS (Antigen Detection, No Centrifugation Recommended) 152
FLUORESCENCE (Visual Identification of the Organisms, Centrifugation Recommended) 152
LATERAL-FLOW CARTRIDGES (Antigen Detection, No Centrifugation Recommended) 153
Larval Nematode Culture 153
HARADA-MORI FILTER PAPER STRIP CULTURE 153
BAERMANN CONCENTRATION 155
AGAR PLATE CULTURE FOR STRONGYLOIDES STERCORALIS 158
Other Methods for Gastrointestinal Tract Specimens 161
EXAMINATION FOR PINWORM (Cellulose Tape Preparations) 161
SIGMOIDOSCOPY SPECIMENS (Direct Wet Smear) 163
SIGMOIDOSCOPY SPECIMENS (Permanent Stained Smear) 166
DUODENAL ASPIRATES 168
Methods for Urogenital Tract Specimens 171
RECEIPT OF DRY SMEARS 171
DIRECT SALINE MOUNT 171
PERMANENT STAINED SMEAR 174
URINE CONCENTRATION (Centrifugation) 176
URINE CONCENTRATION (Nuclepore Membrane Filter) 179
Preparation of Blood Films 181
THIN BLOOD FILMS 182
THICK BLOOD FILMS 184
COMBINATION THICK-THIN BLOOD FILMS 186
RISK MANAGEMENT ISSUES ASSOCIATED WITH BLOOD FILMS 187
USE OF A REFERENCE LABORATORY FOR PARASITE BLOOD DIAGNOSTIC TESTING 188
BLOOD FILM REPORTING WITH ADDITIONAL REPORT COMMENTS 189
BUFFY COAT BLOOD FILMS 189
Blood Stains 190
STAIN OPTIONS 190
GIEMSA STAIN 190
Blood Concentration 194
BUFFY COAT CONCENTRATION 194
KNOTT CONCENTRATION 195
MEMBRANE FILTRATION CONCENTRATION 197
Algorithm 5.1 Procedure for processing fresh stool for the O&P examination 201
Algorithm 5.2 Procedure for processing liquid specimens for the O&P examination 202
...Erscheinungsjahr: | 2021 |
---|---|
Fachbereich: | Tiermedizin |
Genre: | Importe, Medizin |
Rubrik: | Wissenschaften |
Medium: | Taschenbuch |
Inhalt: | 592 S. |
ISBN-13: | 9781683670391 |
ISBN-10: | 1683670396 |
Sprache: | Englisch |
Einband: | Kartoniert / Broschiert |
Autor: | Garcia, Lynne Shore |
Redaktion: | Garcia, Lynne Shore |
Auflage: | 3rd edition |
Hersteller: | Wiley |
Verantwortliche Person für die EU: | Wiley-VCH GmbH, Boschstr. 12, D-69469 Weinheim, product-safety@wiley.com |
Maße: | 253 x 178 x 27 mm |
Von/Mit: | Lynne Shore Garcia |
Erscheinungsdatum: | 22.06.2021 |
Gewicht: | 1,226 kg |